On May 5, 2025, President Donald Trump signed an executive order aimed at boosting domestic production of critical medicines by streamlining regulatory processes. The order directs federal agencies, including the FDA and EPA, to eliminate unnecessary regulations and expedite reviews for pharmaceutical manufacturing, thereby reducing the time and complexity involved in building and expanding facilities in the U.S. This move could enhance national security by ensuring a more resilient supply chain for essential medicines, but it may also face scrutiny over potential environmental and safety oversight reductions.

On May 5, 2025, President Donald Trump signed an executive order aimed at enhancing the safety and security of biological research, particularly focusing on the controversial gain-of-function research. This order halts federal funding for such research conducted by foreign entities in countries with inadequate oversight, like China, and mandates the development of stricter oversight and accountability frameworks for both federally and non-federally funded research. The action could have significant legal and political implications, as it seeks to address biosecurity concerns while potentially altering international research collaborations, and it underscores a shift in U.S. policy toward greater scrutiny and regulation of biological research practices.

President Donald Trump proclaimed May 4-10, 2025, as National Small Business Week, highlighting the crucial role of small businesses in the U.S. economy, which employ nearly half of the private-sector workforce and create the majority of new jobs. His administration aims to support small businesses by cutting regulations, maintaining low taxes, and implementing tariffs to protect against unfair trade practices. These actions are intended to foster economic growth, strengthen local supply chains, and create new opportunities for American entrepreneurs, though they may face legal challenges or political opposition regarding trade policies and regulatory changes.

President Donald Trump has proclaimed May 4 through May 10, 2025, as National Hurricane Preparedness Week to raise awareness about the dangers of hurricanes and encourage preparedness, especially in coastal and at-risk areas. He emphasizes the importance of having an evacuation plan and essential supplies, reflecting on past hurricanes like Katrina and recent ones such as Helene and Milton. Trump has also signed an Executive Order to enhance state and local authorities' roles in disaster resilience and response, aiming to streamline operations and improve community support, which may have legal and political implications by shifting more responsibility to local governments.

President Donald Trump has proclaimed May 2025 as National Mental Health Awareness Month, emphasizing the importance of recognizing and addressing mental health challenges affecting millions of Americans. The proclamation highlights the administration's commitment to improving mental health care, including efforts by the Make America Healthy Again Commission to enhance transparency, research, and access to treatment. This initiative also underscores support for veterans' mental health needs, aiming to create a stronger, healthier future by encouraging awareness and innovative approaches to mental health care across the nation.

President Donald Trump issued an executive order on May 1, 2025, to halt federal funding for National Public Radio (NPR) and the Public Broadcasting Service (PBS). The order argues that taxpayer money should not support media perceived as biased, and instructs the Corporation for Public Broadcasting and other federal agencies to stop both direct and indirect funding. This action could significantly impact public media operations and may provoke legal and political debates over government involvement in media funding and the definition of unbiased reporting.

On May 1, 2025, President Donald Trump signed an executive order to establish the Religious Liberty Commission, aimed at strengthening the protection of religious freedoms in the United States. The commission, comprising up to 14 members from various sectors, will investigate current threats to religious liberty, advise on policy, and produce a comprehensive report by July 4, 2026. This action could stir political debate, as it emphasizes religious freedom in the public sphere, potentially impacting how religious institutions interact with government policies and civil rights issues.

President Donald J. Trump has proclaimed May 8, 2025, as Victory Day for World War II, commemorating the 80th anniversary of the Allied triumph over fascism and national socialism in Europe. This proclamation honors the sacrifices of American soldiers and underscores the commitment to peace and security, reflecting Trump's focus on ending foreign conflicts and maintaining global stability. Politically, this action reaffirms the U.S.'s dedication to liberty and might resonate with veterans and those valuing historical military achievements.

On May 1, 2025, President Donald J. Trump proclaimed May 1 as Loyalty Day and Law Day, U.S.A., emphasizing the importance of the rule of law and loyalty to the Constitution. The proclamation criticizes previous administrations for allegedly politicizing law enforcement and vows to restore fairness and impartiality in federal agencies. This action reinforces a commitment to constitutional principles and aims to unite citizens in reflecting on America's legal heritage, potentially impacting national discourse on justice and governance.

President Donald J. Trump proclaimed May 1, 2025, as a National Day of Prayer, encouraging Americans to reflect on the nation's blessings and the role of prayer in its history. This proclamation emphasizes the administration's commitment to defending religious freedom and combating anti-religious bias through established task forces and the White House Faith Office. The declaration, rooted in a tradition dating back to 1988, underscores the political and cultural significance of faith in America's past and present, potentially influencing national dialogue on religious liberty.

President Donald J. Trump has proclaimed May 3-4, 2025, as National Fallen Firefighters Memorial Weekend to honor the brave firefighters who have lost their lives in the line of duty. The weekend, marked by events in Emmitsburg, Maryland, will see thousands gathering to pay tribute to these heroes and support their families. As part of the observance, the U.S. flag will be flown at half-staff at all federal buildings on May 4, highlighting the nation's gratitude and respect for these selfless individuals.

President Donald Trump has submitted a list of nominations for various key government positions to the Senate for confirmation. These nominations include roles such as United States Attorneys, ambassadors, and high-ranking officials in departments like Homeland Security, Defense, and Education. If confirmed, these appointments could significantly influence the administration's policy directions and operations, and they reflect the President's priorities in areas like national security, education, and international relations. The Senate's response to these nominations could have political implications, particularly if there is opposition or support along party lines.

President Donald Trump has issued an executive order aimed at boosting domestic production of critical medicines by streamlining regulatory processes. This action mandates the FDA, EPA, and other agencies to review and eliminate unnecessary barriers, expediting approvals for pharmaceutical manufacturing in the U.S. The initiative could significantly enhance national security by reducing reliance on foreign pharmaceutical imports, though it may face legal challenges regarding environmental and regulatory standards.

On April 29, 2025, President Donald Trump issued Executive Order 14289 to address the stacking of tariffs on imported goods, aiming to prevent multiple tariffs from cumulatively affecting the same articles. This order seeks to streamline the application of tariffs, ensuring that only the necessary tariffs apply to achieve policy goals, potentially reducing costs for businesses and consumers. Legally, this move could face challenges, as it alters how existing tariffs are administered, and politically, it might stir debate over trade policies and their impact on the economy.

On April 28, 2025, President Donald Trump signed an executive order to enforce English proficiency requirements for truck drivers, aiming to enhance road safety and support the trucking industry. The order mandates the Department of Transportation to revise inspection procedures and ensure compliance with English-language rules, which had not been strictly enforced in recent years. This action may face legal and political scrutiny as it emphasizes language requirements, potentially affecting non-native English-speaking drivers and raising concerns about discrimination and regulatory burdens.