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Improving the Safety and Security of Biological Research

On May 5, 2025, President Donald Trump issued Executive Order 14292, aimed at improving the safety and security of biological research. The order mandates the cessation of federal funding for dangerous gain-of-function research conducted by foreign entities in countries with inadequate oversight, such as China, and establishes a framework for increased oversight and accountability in federally funded life-science research. It also requires the development of a strategy to manage risks associated with non-federally funded research and enhances public transparency and enforcement mechanisms. The purpose of this action is to prevent potential threats to public health and national security while maintaining the United States' leadership in biotechnology and health research.