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Ensuring American Pharmaceutical Supply Chain Resilience by Filling the Strategic Active Pharmaceutical Ingredients Reserve
Executive Order August 19, 2025

Ensuring American Pharmaceutical Supply Chain Resilience by Filling the Strategic Active Pharmaceutical Ingredients Reserve

President Donald Trump issued Executive Order 14336 to enhance the resilience of the American pharmaceutical supply chain by filling the Strategic Active Pharmaceutical Ingredients Reserve (SAPIR). The order directs the Office of the Assistant Secretary for Preparedness and Response (ASPR) to develop a list of approximately 26 critical drugs and to secure a 6-month supply of active pharmaceutical ingredients (APIs) for these drugs, prioritizing domestic production when possible. The ASPR is tasked with preparing the SAPIR repository to receive and maintain these APIs within specified timelines. The order aims to reduce reliance on foreign sources for APIs and bolster national health and security interests.

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Withdrawing The United States From The World Health Organization

Jan 20, 2025

Presidential Action

Withdrawing The United States From The World Health Organization

On January 20, 2025, President Donald Trump issued an order to withdraw the United States from the World Health Organization (WHO). This decision was based on perceived failures by the WHO in handling the COVID-19 pandemic, a lack of necessary reforms, and concerns over disproportionate financial contributions by the U.S. compared to other countries. The order revokes previous actions that re-engaged the U.S. with the WHO and instructs relevant officials to halt funding and reassign personnel involved with the organization. Additionally, the order calls for establishing new structures within the National Security Council to protect public health and biosecurity, and it mandates a review of the U.S. Global Health Security Strategy.