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Delivering Most-Favored-Nation Prescription Drug Pricing to American Patients

On May 12, 2025, President Donald Trump issued Executive Order 14297, aiming to implement most-favored-nation pricing for prescription drugs in the United States. The order seeks to ensure that Americans pay prices for pharmaceuticals that are comparable to those in other developed countries, addressing the current situation where Americans often pay significantly more. It directs the Secretary of Health and Human Services to establish price targets and facilitate direct-to-consumer sales at these prices. Additionally, the order outlines measures to combat global price discrimination and anti-competitive practices, with potential actions including rulemaking, importation of lower-cost drugs, and enforcement against unfair trade practices.