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Unlocking Cures for Pediatric Cancer With Artificial Intelligence

On September 30, 2025, President Donald Trump issued Executive Order 14355, titled "Unlocking Cures for Pediatric Cancer With Artificial Intelligence." This order directs the Make America Healthy Again (MAHA) Commission to collaborate with various federal entities to harness AI technology in combating pediatric cancer, which remains the leading cause of disease-related death among children in the U.S. The initiative aims to improve data infrastructure, enhance predictive modeling, and optimize clinical trials through AI, building on the existing Childhood Cancer Data Initiative. The order also emphasizes increasing federal investment and encouraging private sector engagement in AI-driven pediatric cancer research, while ensuring patient data privacy and interoperability.